​FELIX HOFFMAN- ASPIRIN DISCOVERER.

BONJOUR! So it’s Wednesday, and today’s post is about “This week That year”. 
We all are known to Aspirin but do we know who discovered aspirin?. No …right?

 So the answer to this question is “FELIX HOFFMAN” The man who discovered aspirin and contributed in the era of modern drug.

About Felix Hoffman,

Born: 21 January 1868, Ludwigsburg, Germany

Died: 8 February 1946, Switzerland

Education: Ludwig Maximilian University of Munich (1893), Ludwig Maximilian University of Munich (1891)

Felix Hoffmann was born in Ludwigsburg, Germany, in 1868, the son of an industrialist. After finishing school, he initially aimed for a career as a pharmacist. His work in the field of pharmacy fascinated him so much that he decided to broaden his knowledge in this field by studying chemistry. In 1891 he graduated magna cum laude from the University of Munich. Two years later he earned his doctorate, also magna cum laude, after completing his thesis entitled “On certain derivatives of dihydroanthracene.”  On the recommendation of eventual Nobel Prize laureate Professor Adolf von Baeyer, under whom Hoffmann had studied, he joined “Farbenfabriken vorm. Friedr. Bayer & Co.” in 1894 to work as a chemist in the chemical laboratory.  It was mostly by chance that he made a discovery of historic significance on August 10, 1897. By acetylating salicylic acid with acetic acid, he succeeded in creating acetylsalicylic acid (ASA) in a chemically pure and stable form. The pharmacologist responsible for verifying these results was skeptical at first, yet the extent of this pharmaceutical wonder became clear once several large-scale studies to investigate the substance’s efficacy and tolerability had been completed: Hoffmann had discovered a pain-relieving, fever-lowering and anti-inflammatory substance. The company then worked flat out to develop a cost-effective production process that would allow the promising active ingredient to be supplied as a pharmaceutical product. In 1899 it was launched for the first time under the trade name Aspirin™, initially as a powder supplied in glass bottles. Aspirin™ has made the Bayer name world-famous like no other drug product.  Shortly after the synthesis of acetylsalicylic acid, Hoffmann was made head of the pharmaceutical marketing department. Two years later he was granted full power of attorney. By the time he retired in 1928, his discovery was already a worldwide success. Yet the “inventor” of Aspirin™ remained unknown to the international public. He lived in Switzerland out of the public eye until his death in 1946. Felix Hoffmann was never married and had no children.

ASPIRIN:

Aspirin is a salicylate. It works by reducing substances in the body that cause pain, fever, and inflammation.

Aspirin is used to treat pain, and reduce fever or inflammation. It is sometimes used to treat or prevent heart attacks, strokes, and chest pain (angina).

Aspirin should be used for cardiovascular conditions only under the supervision of a doctor.

Aspirin is not recommended for the following patients:

  • People who have a peptic ulcer
  • Patients with hemophilia or any other bleeding disorder
  • People with a known allergy to aspirin
  • People who are allergic to any NSAIDs, such as ibuprofen
  • Children under 16 years of age (unless under specialist medical supervision.

The following people should be cautious about taking aspirin, and should only do so if the doctor agrees:

  • Patients with asthma
  • Patients with uncontrolled hypertension
  • People who have had a previous peptic ulcer
  • Patients with liver problems
  • Patients with kidney problems

DRAFT BY:

PRAJAKTA PATANKAR.

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